corrosion resistant fiberglass. Its non-conductive characteristic also makes it ideal for use in hazardous areas prone to sparking.In 2023, California and New York proposed banning several food additives that are banned in Europe but legal in the United States. Titanium dioxide was among the five proposed to be banned, but in September, the additive was removed from the list of additives from the California ban list.
CAS registration number: 1345-05-7
Still many experts say the body of research does not support the current health concerns being expressed about titanium dioxide.
Following the EU’s ban on E171, the FDA told the Guardian that, based on current evidence, titanium dioxide as a food additive is safe. “The available safety studies do not demonstrate safety concerns connected to the use of titanium dioxide as a color additive.”
On absorption of UV light, photo-generated titanium dioxide particles create singlet oxygen, superoxide anions (O2-) and hydroxyl radicals (OH-) that are potent free radicals (1,2). Irradiated particles of titanium dioxide can induce oxidative damage to DNA (2) which can lead to the development of mutant cells and skin cancers (3,4,5,6) and lipid peroxidation of essential functions on the cell membrane (7).
Studies have been carried out with both emulsion paints and powder paints, both with clear results on how the use of Lithopone 30% reduces the appearance of algae in the paint once it has been applied (see photos).
Below are selected applications of photocatalytic pollutant decomposition processes on titanium oxide:
1. Self-cleaning surfaces: for the production of glass for spotlights, traffic lights, car mirrors, window panes, for road paints, for covering sound-absorbing screens and tunnel walls.
2. Air cleaning and odor removal: filters that are used in enclosed spaces (e.g. public toilets) or filters for air-conditioning equipment.
3. Water treatment: groundwater treatment installations, water purification installations in the intakes of drinking water from rivers.
4. Self-disinfecting materials: towels, linings, clothing, equipment in hospitals, wall surfaces of operating rooms.
5. Removal of lesions: anti-cancer therapy.
Reasons for listing: Henan Billions Chemical Co., Ltd., a well-known brand of TiO2 factory, a famous trademark in Henan Province, a listed company, a drafting unit of national and industry standards, a high-tech enterprise, advocating the implementation of clean production, focusing on titanium and zirconium fine powder A large-scale inorganic fine chemical enterprise engaged in material R&D and manufacturing.
White powder
The lack of clear regulations and controls explains that P25TiO2NPs are still found in many of the commercialized sunscreens in the market. Some of them are coated to reduce the photoactivity of the anatase form, which is known to be responsible for tissue damage, but not enough studies were made on these coated forms. The anatase photoactivity could trigger the production of reactive oxygen species (ROS) generation, as it was stated before. The ROS are chemically reactive species containing oxygen, such as peroxides, superoxide, hydroxyl radical, and singlet oxygen. They are regularly produced in the biological milieu and counterbalanced by physiological antioxidant defense mechanisms. However, an abrupt increase of ROS may result in non-reversible damage to the skin cells. The effects of coated and uncoated P25TiO2NPs need therefore to be studied, and articles on this topic present different conclusions. [11], [12], [13] Recent literature on this topic found that TiO2NPs inhalation provokes serious genotoxicity and DNA damage [14], [15], [16], [17]. On the other hand, some studies in rats have reported no significant harm to genetic material [18], [19], [20], [21], [22].